Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.18.01 | Pituitary–Basic and IGF-1 | ECE2015

Chronic stress decreases circulating endocannabinoid 2-arachidonoylglycerol in healthy human subjects

Yi Buqing , Nichiporuk Igor , Feuerecker Matthias , Schelling Gustav , Chouker Alexander

Increasing evidence indicates chronic stress plays an important role in a variety of health problems such as the development of autoimmune disease, and the results from mice studies suggest that the central endocannabinoid (eCB) system regulates endocrine and neuronal responses to stress. However, it is unclear how the eCB system responds to chronic stress in healthy humans. A 520-day isolation-and-confinement study simulating an interplanetary spaceflight mission to Mars prov...